In vitro conditions affect biomass and bioactive compound productions in bioreactors. Biomass production of hairy roots of artemisia annua and arachis hypogaea. As nanobiotechnology has improved the bioactive extraction process. The medium salt strength is one of the key factors that affect plant metabolites. During the bioreactor culture of plant cells, tissues, or organs for metabolite production, factors affecting biomass and bioactive compound accumulation in a culture should be explored to optimize a bioreactor culture system. The use of chemical elicitors is particularly important in industrialscale bioreactors since the production of both biomass and phytochemicals often decreases. Future perspectives of biomass and bioactive compound production have.
Bioreactor cultures are used to enhance biomass and bioactive compound production in plant cell or organ culture jeong et al. Through large scale bioreactor cultures article october 2014 with 232 reads. Various parameters, such as inoculum density 315 g l1 and duration of growth 17 weeks, were optimized in a 3l airlift bioreactor. The biosynthesis of alkaloids may be affected by the types and concentrations of. The utilization of bioreactor is an exciting preposition in medicinal plant biotechnology for shoot multiplication, and production of bioactive metabolites has recently progressed exhibiting a considerable development towards cultivation of plants for metabolite production using cost effective, easily available bioreactor devices 610.
Culture vessels to bioreactors article august 2014 with 452 reads. School of biosciences and technology, vit university, vellore 632014, tamil nadu, india. In the last decade, the industrial applications of bioactive compounds. The phenolics production of roots cultured in flasks and bioreactors showed slightly decline from 1 to 2 week then it continued to increase. These compounds include potent bioantioxidants, provitamins, and safe colourants that are in high demand by pharmaceutical, cosmetic and food industries. It is actually full of knowledge and wisdom you are going to like the way the blogger publish this book. Kf525 and the need to maintain a relatively high cn ratio, it was not possible to improve calcaride a production by increasing biomass production by kf525 or by using fedbatch strategies. Chapter 7 production of biomass and bioactive compounds from cell suspension cultures of panax quinquefolium l. Production of biomass and secondary metabolites from plant cell. Current approaches toward production of secondary plant metabolites. A few species of unicellular algae called carotenogenic microalgae mainly the representatives of chlorophyta. Production of biomass and bioactive compounds using bioreactor technology.
Production of biomass and bioactive compounds using. For example, by adding methyl jasmonate to the medium on day 28, cui et al. Production of biomass and bioactive compounds from cell. Therefore, nitrate rather than ammonium nitrogen was more essential not for only biomass production but also for bioactive compound production in e. Download it once and read it on your kindle device, pc, phones or tablets. Enhanced productivity of biomass and bioactive compounds. The production of biomass and bioactive compounds in the adventitious roots per 1 l medium was calculated based on. The traditional technique of industrial production of car particularly.
Plant cell and tissue culture technology has been considered as a powerful tool. Use features like bookmarks, note taking and highlighting while reading production of biomass and bioactive compounds using bioreactor technology. In recent decades, plant cell, tissue and organ cultures have emerged as an alternative over whole plant cultivation for the production of valuable secondary metabolites. Research is currently exploring the possibility of producing these alkaloids using biotechnological methods, including in vitro cultures. Adventitious root culture of morinda citrifolia in bioreactors for production of. The nitrogen source may also be important, but was not systematically investigated. Production of adventitious root biomass and bioactive. Protocorm culture of dendrobium candidum in balloon type. Volatiles residence time in a fluidized bed reactor. Considering these, we have designed a balloon type bubble bioreactor btbb, which was found effective to overcome foaming and cell growth on the wall of the reactor vessel, and also found to be reliable for enhancing production of biomass and bioactive compounds of different high value medicinal plants paek et al. Furthermore, the pscc technology provides a rapid biomass growth. Biotechnological production of bioactive compounds 1st. Kinsenoside and polysaccharide production by rhizome.
Part ii deals with the production of biomass and bioactive com. Tremendous efforts have been made to commercialize the production. Part i describes bioreactor designing advantages and limitations of bioreactor cultures. Pdf carotenoids comprise a diverse group of natural biomolecules with a plethora. Furthermore, the pscc technology provides a rapid biomass growth and enables the production of bioactive compounds, making their scalability to industrial bioreactors easier 2, satisfying. Production of biomass and bioactive compounds using bioreactor. Poojadevi sharma, sonal sharma, sheetal yadav, anshu srivastava, indira purohit and neeta shrivastava, plant derived bioactive molecules. Bioreactor technology for large scale cultivation of plant cell suspension cultures and production of bioactive compounds dr. Bioreactor cultures have been established for the production of embryogenic biomass and bioactive compounds. Biomass production of hairy roots of artemisia annua and. Biomass production of gynura procumbens adventitious roots.
Dendrobium candidum protocorm suspension cultures in balloon type bubble bioreactors have been established enhanced accumulation of biomass and bioactive compounds in bioreactor cultures was achieved. Production of biomass and bioactive compounds from. Ali mb, yu kw, hahn ej, paek ky 2006b methyl jasmonate and. Cyclodextrinelicited bryophyllum suspension cultured cells ncbi. A bioreactor with helix impeller has been designed and developed at nuclear. Biotechnological production of bioactive compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. The results of the current study are useful for the production of d. Bioreactor culture expends exploitation on bioactive compounds for industries.
Production of adventitious root biomass and bioactive compounds from hypericum perforatum l. Production of biomass and bioactive compounds from adventitious. Scaledup production of biomass and bioactive compounds. Highlights adventitious root culture is an attractive mean of bioactive compound production. Read production of biomass and bioactive compounds from cell and organ cultures of valueadded medicinal plants in bioreactors, journal of biotechnology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Production of biomass and bioactive compounds using bioreactor technology the bioactive compounds of plants have worldwide applications in pharmaceutical, nutraceutical and food industry with a huge market. Journal of bioscience and bioengineering, 1196, 712717. Kyungju lee, youngki park, jayoung kim, taekkyu jeong, kyungseop yun, keeyoeup paek and soyoung park, production of biomass and bioactive compounds from adventitious root cultures of polygonum multiflorum using airlift bioreactors, journal of plant biotechnology, 42, 1. Production of bioactive compounds in biorefineries. Influence of inoculum density and aeration volume on. In the present study, we identified optimal conditions for adventitious root cultures of these plants to optimize the scaleup of the production of biomass and bioactive compounds. Paek ky, murthy hn, jianjiang zhong 2014 production of biomass and bioactive compounds using bioreactor technology. The bioactive compounds of plants have worldwide applications in pharmaceutical, nutraceutical and food industry with a huge market. Bioreactor shoot cultures of rhododendron tomentosum.
To determine the exact stage at which the maximum biomass is produced and to evaluate the accumulation of bioactive compounds, fresh roots were inoculated at densities varying from 2. In practical terms, pscc technology offers several advantages for the production of bioactive. Plants are the major source of secondary metabolites which are used as pharmaceu ticals, avours, fragrances, colouring agents, food additives and agrochemicals. Tremendous efforts have been made to commercialize the production of plant metabolites by employing plant cell and organ cultures in bioreactors. In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the production of biomass and bioactive compounds using bioreactors. Suitability of bench scale bioreactor system for shoot. In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the. Effect of nitrogen source on biomass and bioactive. This book provides recent progresses and limitations of production of biomass and bioactive compounds using bioreactor technology as mentioned above. Fulzele nuclear agricuttura and biotechnology division bhabha atomic research centre abstract a bioreactor with heliximpellerhas beendesignedand developedat nuclearagricultureand. Production of biomass and bioactive compounds using bioreactor technology 1 edition by keeyoeup paek, hosakatte niranjana murthy, jianjiang zhong production of biomass and bioactive compounds using bioreactor technol. Production of biomass and ginsenosides from adventitious. Altmetric production of biomass and bioactive compounds.
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